Celebs Who Spoke About GLP-1s—What They Actually Said (No Rumors, Just Receipts)
GLP-1 medications (Ozempic/Wegovy, Mounjaro/Zepbound) jumped from whispers to headlines fast.
If you’ve heard stars mention them and wondered how that translates to real-life care, services like g-plans.com connect people with GLP-1 telehealth support and day-to-day nutrition planning—useful context for what you’ll read below. (Information only—talk to your clinician.)
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We kept this easy, verified, and interesting: only celebs who’ve publicly addressed GLP-1s themselves, a quick “what they said,” a bit you might not have seen in the usual listicles, and where you’ve seen them on screen.
Oprah Winfrey — the conversation changed when she spoke
What she said/did: Oprah Winfrey fronted a prime-time special that treated prescription weight-loss drugs like a serious health topic, not a gossip item—and later acknowledged using a weight-loss medication herself. That shifted the tone industry-wide from coy to candid.
A detail you don’t always see: Publicists started answering one GLP-1 question cleanly and moving interviews back to craft—Oprah’s framing made that acceptable.
Where you’ve seen her: The Color Purple (Oscar-nominated), Lee Daniels’ The Butler, producer on the 2023 musical film The Color Purple.
Amy Schumer — Wegovy didn’t work for her; Mounjaro did
What she said: Amy Schumer’s been blunt that Wegovy/Ozempic made her very nauseated, so she stopped; later, she said Mounjaro fit better and has shared ongoing health updates.
A detail you might have missed: Her openness included other medical contexts (e.g., perimenopause/HRT workups), which helps explain the trial-and-error arc rather than a simple “before/after.”
Where you’ve seen her: Trainwreck, I Feel Pretty.
Chelsea Handler — “I didn’t realize I was on Ozempic” (and then quit)
What she said: A doctor gave her Ozempic, Chelsea Handler later realized what it was, and stopped—using the story to warn against treating prescriptions like trends.
A detail you don’t often get: Her version spotlights informed consent as much as results—rare in celeb soundbites.
Where you’ve seen her: This Means War (scene-stealing BFF).
Sharon Osbourne — when “success” went too far
What she said: Sharon Osbourne lost a dramatic amount on Ozempic, then publicly called herself “too gaunt,” warning others (especially teens) to be cautious and talking about how hard it was to regain healthy weight.
A detail you might have missed: She’s framed her experience as a PSA, not a glam reveal—one of the clearer “here’s what I regret” celebrity accounts.
Where you’ve seen her: Mostly TV (The X Factor, The Talk), but her candor makes this list.
Tracy Morgan — from punchline to precise routine
What he said: Tracy Morgan confirmed using Ozempic, joked on air about gaining weight on it, then clarified he was kidding—adding a practical nugget: he doses every Thursday.
A detail you don’t usually see: That specific dose-day mention (Thursday) is the kind of concrete scheduling celebs rarely share—and it explains how some people anchor weekly meds around work.
Where you’ve seen him: The Longest Yard, Cop Out, voice roles in Rio.
Rosie O’Donnell — steady Mounjaro updates with receipts
What she said: Rosie O’Donnell’s repeatedly credited Mounjaro (for diabetes) and posted progress photos/captions over time—at one point even calling it “a life saver.”
A detail you might have missed: The breadcrumb trail (photos + dates + captions) is unusually documentary-style for a celeb—more than a single interview or selfie drop.
Where you’ve seen her: A League of Their Own, Sleepless in Seattle.
Golnesa “GG” Gharachedaghi — rare specificity in numbers
What she said: Golnesa “GG” Gharachedaghi publicly shared starting around 138 lbs, dropping to roughly 110 lbs on semaglutide, and then cutting back because it went further than she intended.
A detail you might have missed: That granular, on-camera adjust-the-plan moment (not just “I started”/“I finished”) is exactly what most celebrity posts skip.
Where you’ve seen her: Shahs of Sunset (reality TV, not film—still one of the most transparent GLP-1 timelines).
Elon Musk — two words that turbocharged awareness
What he said: In a quick reply online, Elon Musk credited “fasting” + “Wegovy”—not a press tour, just a post—but it sent semaglutide into mainstream chatter beyond Hollywood.
A detail you might have missed: That casual mention helped normalize seeing GLP-1 talk outside fitness or entertainment contexts.
Where you’ve seen him: Cameos/appearances, but he’s here because the post moved the culture needle.
What these celebs actually credit GLP-1s for… and what they don’t
- Do: help curb appetite and support weight/diabetes management when supervised by a clinician (you’ll see words like “nausea” early on, “less hungry,” and “more manageable”).
- Don’t: replace the boring fundamentals. Even the most candid posts still hinge on sleep windows, steady hydration, and predictable meals—the un-sexy stuff that keeps press tours coherent and set days safe.
